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CAS 968-93-4 Anabolic Androgenic Steroids Testolactone for Anti neoplastic

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CAS 968-93-4 Anabolic Androgenic Steroids Testolactone for Anti neoplastic

CAS 968-93-4 Anabolic Androgenic Steroids Testolactone for Anti neoplastic
CAS 968-93-4 Anabolic Androgenic Steroids Testolactone for Anti neoplastic CAS 968-93-4 Anabolic Androgenic Steroids Testolactone for Anti neoplastic CAS 968-93-4 Anabolic Androgenic Steroids Testolactone for Anti neoplastic CAS 968-93-4 Anabolic Androgenic Steroids Testolactone for Anti neoplastic

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CAS: 968-93-4 MF: C19H24O3
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Antineoplastic Steroids Testolactone

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Anabolic Androgenic Steroids Testolactone

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CAS 968-93-4 Testolactone

Anabolic Androgenic Steroids Testolactone CAS 968-93-4 for Antineoplastic

 

Testolactone
 

Product Name: Testolactone 
Synonyms: TESTOLACTONE;1,2,3,4,4a,4b,7,9,10,10a-decahydro-2-hydroxy-2,4b-dimethyl-7-oxo-1-phenanthren;1,2-dehydrotestololactone;1,2-didehydro-testololacton;17alpha-oxo-d-homo-1,4-androstadiene-3,17-dione;17-secoandrosta-1,4-dien-17-oicacid,13-hydroxy-3-oxo-1delta-lactone;1-dehydrotestololactone;delta(1)-dehydrotestolactone 
CAS: 968-93-4 
MF: C19H24O3 
MW: 300.39 
EINECS: 213-534-6 

Usage Antineoplastic; non-selective steroidal aromatase inhibitor that prevents the conversion from androgen to estrogen. Used in in the treatment of familial male precocious puberty. An effective anti-tumor agent. 

Testolactone is a synthetic antineoplastic agent that is structurally distinct from the androgen steroid nucleus in possessing a six-membered lactone ring in place of the usual five-membered carbocyclic D-ring. Despite some similarity to testosterone, testolactone has no in vivo androgenic effect.

 

Testolactone Description

 

(1). Testolactone - classified as an antineoplastic agent

Testolactone is approved by the United States Food and Drug Administration (FDA), and its cost usually is covered by insurance. It is classified as an antineoplastic agent, which means that it stops or slows the growth of malignant cells. One advantage of testolactone is that, although it is related to testosterone, it does not cause women to develop male characteristics such as a deep voice or facial hair.

 (2). Related to the male hormone testosterone

Testolactone is related to the male hormone testosterone. The way in which it inhibits the growth of breast cancer cells is not clear. However, it is known that the hormone estrogen stimulates the growth of some breast cancer cells, and testolactone seems to interfere with estrogen production. The resulting reduction in estrogen levels may slow the growth of breast cancers sensitive to this hormone.

 (3). A palliative treatment

In breast cancer, testolactone is a palliative treatment. This means that it helps relieve symptoms, but does not cure the cancer. It is effective only in about 15% of the women who take it. In these women, however, it helps reduce the size of half or more tumors. Normally testolactone is used along with other chemotherapy drugs for fighting advanced breast cancer.

 (4). Dosage

Testolactone comes as a 50 mg tablet. The dose will depend on the patient's body weight and her general health, as well as other drugs she may be taking. However, a standard dose is 250 mg (5 tablets) four times a day for three months. It takes at least several weeks before the drug begins to be effective. Tablets should be stored at room temperature.

 

Related Female Hormone Steroids:
 
Estradiol Estrone Hydrocortisone
Estradiol valerate Estriol Hydrocortisone acetate
Estradiol benzoate Nylestriol Meprednisone
Estradiol cypionate Diethylstilbestrol Prednisone acetate
Estradiol enantate HEXESTROL Bentelan
Ethynyl estradiol Progesterone Betamethasone
Algestone acetophenide Medroxyprogesterone acetate Clobetasol propionate
Ethisterone Norethindrone Halobetasol propionate
19-Norethindrone acetate Mifepristone Deflazacort
Norethisterone Enanthate Methyldienedione Tazarotene
Ethynodiol diacetate Eplerenone Ecdysone
Pregnenolone acetate Levonorgestrel Desloratadine
Lynestrenol Allylestrenol Prednisolone phosphate sodium
Chlormadinone acetate Dienogestrel Fluorometholone Acetate
Cyproterone acetate Drospirenone Dexamethasone Acetate
Megestrol acetate Pregnenolone Dexamethasone Sodium Phosphate
Melengestrol acetate Mometasone furoate Dexamethasone palmitate
Betamethasone acetate Beclomethasone dipropionate Fluocinolone acetonide
Betamethasone Dipropionate Betamethasone 17-valerate  

 
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