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topical anesthetic medications,
medicine raw material
Local Anesthetic Drugs Lidocaine / Xylocaine CAS 137-58-6 Pharmaceutical Raw Powder
Product Name: Xylocaine
Synonyms: 2-(Diethylamino)-2',6'-acetoxylidide;2-(diethylamino)-2’,6’-acetoxylidide;2-(diethylamino)-n-(2,6-dimethylphenyl)-acetamid;2',6'-Acetoxylidide, 2-(diethylamino)-;6’-acetoxylidide,2-(diethylamino)-2;Acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)-;Acetamide,2-(diethylamino)-N-(2,6-dimethylphenyl)-;a-Diethylamino-2,6-acetoxylidide
Chemical Properties solid
Usage Lidocaine (Alphacaine)is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.  Histamine is responsible for many features of allergic reactions. Lidocaine (Alphacaine)is a second-generation antihistamine agent closely st
Usage Antiarrhythmic Agents, Anesthetics
Biological Activity Anasthetic and class Ib antiarrhythmic agent.? Blocks voltage-gated sodium channels in the inactivated state.
1. Lidocaine, xylocaine, or lignocaine is a common local anesthetic and class-1b antiarrhythmic drug. Lidocaine is used topically to relieve itching, burning, and pain from skin inflammations, injected as a dental anesthetic, or as a local anesthetic for minor surgery.
2. It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic healthcare system.
3. Lidocaine is the most important class-1b antiarrhythmic drug; it is used intravenously for the treatment of ventricular arrhythmias (for acute myocardial infarction, digoxin poisoning, cardioversion, or cardiac catheterization) if amiodarone is not available or contraindicated.
4. Lidocaine should be given for this indication after defibrillation, CPR, and vasopressors have been initiated. A routine prophylactic administration is no longer recommended for acute cardiac infarction; the overall benefit of this measure is not convincing.
Lidocaine Usage Fields:
1. The efficacy profile of lidocaine as a local anesthetic is characterized by a rapid onset of action and intermediate duration of efficacy. Therefore, lidocaine is suitable for infiltration, block, and surface anesthesia. Longer-acting substances such as bupivacaine are sometimes given preference for subdural and epidural anesthesias; lidocaine, though, has the advantage of a rapid onset of action.
2. Epinephrine (adrenaline) vasoconstricts arteries, reducing bleeding and also delays the resorption of
lidocaine, almost doubling the duration of anaesthesia. For surface anesthesia, several available
formulations can be used e.g. for endoscopies, before intubations, etc. Buffering the pH of lidocaine
makes local freezing less painful. Lidocaine drops can be used on the eyes for short ophthalmic
3. Relative insensitivity to lidocaine is genetic. In hypokalemic sensory overstimulation, relative
insensitivity to lidocaine has been described in people who also have attention deficit hyperactivity
disorder.In dental anesthesia, a relative insensitivity to lidocaine can occur for anatomical reasons
due to unexpected positions of nerves. Some people with Ehlers-Danlos syndrome are insensitive to lidocaine.
4. Lidocaine, along with ethanol, ammonia, and acetic acid, has also been proven to be effective in
treating jellyfish stings, both numbing the affected area and preventing further nematocyst discharge.
|Propitocaine hydrochloride||CAS: 1786-81-8|
|Tetracaine hydrochloride||CAS: 136-47-0|
|Procaine hydrochloride||CAS: 51-05-8|
|Pramoxine hydrochloride||CAS: 637-58-1|
|Proparacaine hydrochloride||CAS: 5875-06-9|
|Benzocaine hydrochloride||CAS: 23239-88-5|
|Lidocaine hydrochloride||CAS: 73-78-9|
|Articaine hydrochloride||CAS: 23964-57-0|
|Levobupivacaine hydrochloride||CAS: 27262-48-2|
|Ropivacaine hydrochloride||CAS: 132112-35-7|
|Dibucaine hydrochloride||CAS: 61-12-1|
|Bupivacaine hydrochloride||CAS: 14252-80-3|
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1. We have experience in exporting steroids, as you know, EU places much emphasis on them, and you must find a experienced partner who will assure you;
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3. Package: Professional packing with professional materials
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