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Spironolactone 52-01-7 treatment of urinary infection Ineffective diuretic pharmaceutical grade

Spironolactone 52-01-7 treatment of urinary infection Ineffective diuretic pharmaceutical grade

  • Spironolactone 52-01-7 treatment of urinary infection Ineffective diuretic pharmaceutical grade
  • Spironolactone 52-01-7 treatment of urinary infection Ineffective diuretic pharmaceutical grade
Spironolactone 52-01-7 treatment of urinary infection Ineffective diuretic pharmaceutical grade
Product Details:
Place of Origin: steroidraw@chembj.com
Brand Name: whatsapp:+8618578209857
Certification: SGS,ISO9001,UKAS
Model Number: 52-01-7
Payment & Shipping Terms:
Minimum Order Quantity: 10g
Price: Negotiation
Packaging Details: Special disguised packaging or as your demand
Delivery Time: within 12hours after payment
Payment Terms: T/T, ,
Supply Ability: 1000 Kilogram/Kilograms per Month
Contact Now
Detailed Product Description
Product Name: Spironolactone English Synonyms: Aldactone;Antisterone;spirolactone;7-alpha-Acetylthio-3-oxo-17-alpha-pregn-4-ene-21,17-beta- Carbolactone
CAS: 52-01-7 Formula: C24H32O4S
MW: 416.5735 Assay: 98.99%
Appearance: White Or Almost White Fine Crystalline Powder Usage: Used As A Diuretic
High Light:

pharma raw materials

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Pharmaceutical Grade Steroids Diuretic Powder Potassium-Sparing Diuretics Spironolactone

 

1. Spironolactone Quick Detail:

English name: Spironolactone

Synonym: Aldactone;Antisterone;spirolactone;7-alpha-Acetylthio-3-oxo-17-alpha-pregn-4-ene-21,

17-beta- carbolactone
CAS: 52-01-7
EINECS Number: 200-133-6
Formula: C24H32O4S
MW: 416.5735
Molecular Structure:
Density: 1.24g / cm3
Melting point: 198-207 ℃ (dec.)
Boiling point: 597 ° C at 760 mmHg
Flash Point: 302.2 ° C
Water-soluble: practically insoluble
Vapor Pressure: 3.24E-14mmHg at 25 ° C
Melting point 198-207 ° C (dec.)
Specific rotation -37 ° (c = 1, CHCl3)
Water-soluble practically insoluble

Assay:98.99%

Appearance: White or almost white fine crystalline powder
Uses:Used as a diuretic

 

2. Spironolactone Description:

 

Spironolactone and commonly shortened simply to "spiro") ,marketed mainly under the brand name 

Aldactone in most countries, is a synthetic, steroidal antimineralocorticoid,antiandrogen, and, to a 

lesser extent, progestin. It belongs to a class of pharmaceutical drugs known as potassium-sparing diuretics, and is used primarily as a diuretic and antihypertensive in the treatment of heart 

failure andhypertension. As a secondary use, spironolactone is also frequently employed off-label 

for the purpose of reducing elevated or unwanted androgen levels and activity in the body, such 

as in the treatment of hyperandrogenism in women and, especially, as a component of hormone 

replacement therapy for trans women.

 

4. Spironolactone COA:

ITEMS

STANDARDS

RESULTS

Appearance (Ph.Eur.)

A white or yellowish-white powder

White powder

Solubility (Ph.Eur.)

Practically insoluble in water, soluble 

in ethanol (96%)

Complies

Identification

A. IR –spectrum (Ph.Eur.)

Meet the requirement

Complies

A. IR –spectrum (USP)

Meet the requirement

Complies

B. TLC (Ph.Eur.)

Meet the requirement

Complies

B. UV absorption (USP)

Meet the requirement

Complies

C. Colour reaction (Ph.Eur.)

Meet the requirement

Complies

C. Precipitate reaction (USP)

Meet the requirement

Complies

Specific optical rotation

-41°~-46°

-42.8°

(Ph.Eur.)

-41°~-45°

-42.9°

(USP)

 

 

Sulphated ash (Ph.Eur.)

≤0.1%

0.00%

Related substances (Ph.Eur.)

Impurity A

≤0.2%

N.D.

Impurity B

≤0.3%

N.D.

Impurity C

≤0.2%

N.D.

Impurity D

≤0.15%

N.D.

Impurity E

≤0.3%

N.D.

Impurity I

≤0.5%

0.05%

Any unspecified impurity

≤0.10%

Complies

Total

≤0.7%

0.13%

Ordinary impurities (USP)

≤2.0%

Complies

Free thiol compounds (Ph.Eur.)

≤0.05mL

Complies

Free mercapto compounds (USP)

≤0.10mL

Complies

Chromium (Ph.Eur.)

≤50ppm

Complies

Assay

97.5%~102.0%

100.90%

HPLC (Ph.Eur.)

97.5%~103.0%

99.60%

HPLC (USP)

 

 

Residual solvent (In-house)

≤3000ppm

90ppm

Methanol

≤720ppm

≤LOD (0.0046ppm)

Tetrahydrofuran

≤880ppm

≤LOD (0.23ppm)

DMF

 

 

Particle size (In-house)

95% ≤ 20 microns

Complies

Conclusion

Compiles with EP7/USP35

 

5. Spironolactone Product Picture:

Spironolactone 52-01-7 treatment of urinary infection Ineffective diuretic pharmaceutical grade 0

 

6. Spironolactone Applications:

 

Spironolactone is competitive inhibition of aldosterone drugs, drug itself is not active, role is diuresis 

and endogenous competitive aldosterone antagonist and happen, belongs to the potassium diuretics.

 

 

7. Pharmaceutical Raw Material we supply:

 

Gamma-Butyrolactone(GBL) 

the intermediate of plant growth stimulator and insecticide

Cabergoline 

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treat different types of medical problems

Isotretinoin 

CAS 4759-48-2

treat severe cystic acne

Spironolactone

CAS 52-01-7

Used as a diuretic

Minoxidil

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an antihypertensive vasodilator medication

Phenacetin

CAS 62-44-2

a cutting agent to adulterate cocaine 

Pramipexole Hydrochloride

CAS 191217-81-9 

Parkinson's disease drug

Ropinirole Hydrochloride

CAS 91374-20-8 

Used in the treatment of Parkinson's disease 

Pramiracetam

CAS 68497-62-1

nootropic drug derived from piracetam

Zanamivir Hydrate

CAS 139110-80-8 

Influenza viral neuraminidase inhibitor

Melatonin 

CAS 73-31-4 

theentrainment of the circadian rhythms

Methyl Synephrine 

Hydrochloride 

CAS 365-26-4

can promote thermogenesis

Benzyl Alcohol 

CAS 100-51-6    

a good middle boiling point solvent

Benzyl Benzoate

CAS 120-51-4    

used as an acaricide, scabicide, and pediculicide

Ethyl Oleate

CAS 111-62-6

Can be used as pharmaceutical material

 

8. Competitive Advantages:

 

Pre-sale service

1. Technical consultancy, to help customer know about the properties, features, quality, production and supply of the product they want.

2. Technical information and documents, such as COA, test report, sample etc.

3. Customers are welcome to visit our factory and negotiate with us at any time.

 

Sales service

1. Sign contract with customer, negotiating price, quality, delivery and other terms.

2.Answer the questions concerning properties, mechanism, application, quality, attention, usage etc. of the product.

3. Production schedule and on time delivery after signing contract.

 

After-sale service

1. Technical consultancy during use of the product.

2. Customer can return or exchange the merchandise with us if they need to change purchase plan due to some reasonable reasons, on condition that the product is not damaged.

3. If quality problems occur during normal use, please send us written information and documents, and we will respond within 24-48 hours.

 

Our R&D (research and development) center has around 1,000 square meters synthesis and testing laboratory, meets industrial standards, equipped with first class research facilities and powerful technical team.

Contact Details
SBS BIOTECH CO.,LTD

Contact Person: Alex

Tel: 86-18171373082

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