Payment & Shipping Terms:
|Character:||White Needle-Like/ 99% 96%||Use:||Applied In Toothpaste, Food, Artificial Joints Research, Artificial Bones, Water Filtration|
Nano Hydroxyapatite HAP/ HA(1306-06-5) for Toothpaste, Food, Artificial Joints Research, Water Filtration
|EPA Substance Registry System||Hydroxylapatite (Ca5(OH)(PO4)3)(1306-06-5)|
|Synonyms||CALCIUM PHOSPHATE HYDROXIDE;CALCIUM PHOSPHATE TRIBASIC;CALCIUM HYDROXIDE PHOSPHATE;CALCIUM HYDROXYAPATITE;BONE ASH;BEEF BONE POWDER;APATITE HAP, MONOCLINIC;HA, BOVINE|
|Use||Applied in Toothpaste, Food, Artificial Joints Research, Artificial Bones,
Hydroxylapatite can be found in teeth and bones within the human body. Thus, it is commonly used as a filler to replace amputated bone or as a coating to promote bone ingrowth into prosthetic implants. Although many other phases exist with similar or even identical chemical makeup, the body responds to them very differently. Coral skeletons can be transformed into hydroxylapatite by high temperatures; their porous structure allows relatively rapid ingrowth at the expense of initial mechanical strength. The high temperature also burns away any organic molecules such as proteins, preventing an immune response and rejection.
Many modern implants, e.g. hip replacements, dental implants and bone conduction implants, are coated with hydroxylapatite. It has been suggested that this may promote osseointegration. Porous hydroxylapatite implants are used for local drug delivery in bone. It is also being used to repair early lesions in tooth enamel.
In spite of attractive biological properties hydroxylapatite , materials based thereon have some drawbacks, such as low bioresorption rate in vivo, poor stimulating effect on the growth of new bone tissues, low crack resistance and small fatigue durability in the physiological environment. The application of modified hydroxylapatite opens up the opportunities for the preparation of artificial bone substances for implants and a large variety of drugs for curing different lesions of bone, soft and mucous tissues of the individual. A promising method of modification is the introduction of uorine or silicon into the primary structure with the formation of uorine- or silicon-substituted Hydroxylapatite. The introduction of uorine increases the resistance to biodegradation and improves the adsorption of proteins and adhesion of the coating to the metal substrate.
Hydroxylapatite deposits in tendons around joints resulting in the medical condition calcific tendinitis.
Microcrystalline hydroxylapatite (MH) is marketed as a "bone-building" supplement with superior absorption in comparison to calcium. It is a second-generation calcium supplement derived from bovine bone. In the 1980s, bone meal calcium supplements were found to be contaminated with heavy metals, and although the manufacturers claim their MH is free from contaminants, people are advised to avoid it because its effect in the body has not been well-tested. However, the limited tests seem to show positive results. A 1995 randomized placebo-controlled study of 40 people in Europe found that it was more effective than calcium carbonate in slowing bone loss. A 2007 randomized double-blind controlled study of an MH supplement called the Bone Builder found significant positive effects in bone mineral density (BMD) compared to control. Hydroxylapatite has been used by Noel Fitzpatrick to facilitate bionic development in animals, by coating steel rods in hydroxylapatite to encourage natural growth of skin around it. As a component of nanocomposites, hydroxylapatite is finding uses as a potential new bone replacement materials.
Models and Specifications:
|Product Name||Hydroxyapatite Nano|
|Average Particle Size||60nm|
|Sulfate||0.048 % max||0.043%|
|Chloride||0.05 % max||0.04%|
|Heavy metals||10 ppm max||9.5|
|Loss on drying||1.0 % max||0.87%|
|Product Name||Hydroxyapatite Nano|
|Average Particle Size||20nm|
|Sulfate||0.048 % max||0.025%|
|Chloride||0.05 % max||0.02%|
|Heavy metals||10 ppm max||7|
|Loss on drying||1.0 % max||0.75%|
Other Models Available:
|MHAP02||Needle-like||40||96%||General Grades, Protein Isolate, Simple Artificial bones research|
|MHAP03||Needle-like||20||97.5%||Low purity artificial bones, artificial joints, bone substitutes, foods, toothpastes|
|MHAP04||Needle-like||20*150||99%||High purity artificial bones, joints|
|MHAP05||Clavate||30*100||99%||High purity artificial bones, joints, medicine research|
|MHAP06||Spherical||12um||99%||Especially for artificial bones and artificial joints coating|
1. Quality guarantee: We are a leading professional factory in China special in pharmaceuticals for more than 14 years(founded in 2001). Our products exported to all over the world.
2. Discreet packing: The best-suited package would be selected to pass customs 100% guaranteed. The package updates would be closely tracked and timely informed. Once any problem found, the package would be reshipped for you.
3. Alternative delivery ways: by land, by air, by sea, by express(FedEx,UPS,DHL,EMS etc.). The most cost-effecient forwarder would be recommanded.
4. Considerate after-service: 24/7 at service for you. Any problem would be valued and solved ASAP.
5. COA (by HPLC) or TDS and sample are available at any time.
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