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Pure Pharmaceutical Raw Material Pregabalin for Treatment Antiepileptic

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Pure Pharmaceutical Raw Material Pregabalin for Treatment Antiepileptic

China Pure Pharmaceutical Raw Material Pregabalin for Treatment Antiepileptic supplier
Pure Pharmaceutical Raw Material Pregabalin for Treatment Antiepileptic supplier Pure Pharmaceutical Raw Material Pregabalin for Treatment Antiepileptic supplier

Large Image :  Pure Pharmaceutical Raw Material Pregabalin for Treatment Antiepileptic

Product Details:

Place of Origin: china manufactuer
Brand Name: Pharmaceutical
Certification: KOSHER,ISO9001, ISO14000
Model Number: 148553-50-8

Payment & Shipping Terms:

Minimum Order Quantity: 10g
Price: $1.5-45/g
Packaging Details: Special disguised packaging or as your demand
Delivery Time: within 12hours after payment
Payment Terms: Western Union, MoneyGram, T/T, Bitcoin
Supply Ability: 2000kg/Month
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Detailed Product Description
Product Name: Pregabalin CAS: 148553-50-8
Molecular Formula: C8H17NO2 Molecular Weight: 159.23
Melting Point: 194-196 Degree Centigrade Boiling Point: 274 Degree Centigrade At 760 Mmhg

 

 

product name: Pregabalin

CAS:148553-50-8
Molecular Formula: C8H17NO2
Molecular Weight :159.23
Melting Point:194-196 degree centigrade
Boiling  Point:274  degree centigrade at 760 mmHg
Flash Point:119.5  degree  centigrade
Density: 0.997 g/cm3
Assay :99%
Appearance: White or faint white crystal powder
Function: The drug is in the development of one of the most promising drug in epilepsy   drug treatment, the better curative effect and  drug delivery is more convenient.                 It can also be used in the treatment of pain and anxiety.

Usage: A GABA Analogue Used as an Anticonvulsant

Delivery: Sent out Within 12 Hours After Payment Confirmed

Shipping: Express Courier(EMS, DHL, UPS, TNT, FedEx)
Export Markets :Global
Packing: 25kg/ Paper Barrel or as Your Demand

HS Code: 29144000

Product Categories: APIs;Miscellaneous Biochemicals;Intermediates & Fine Chemicals;

Neurochemicas;Pharmaceuticals; compounds





 
 

 

 

 

 

 

 

 

 

                                

 

 

 



 


 

 

 

 

 

 

 

 

 

 

 

2. Product Description:
                                      Enantiomer of Pregabalin. A GABA analogue used as an anticonvulsant. Anxiolytic analgesic 

used to treat peripheral neuropathic pain and fibromyalgia.Pregabalin is an anticonvulsant drug used for neuropathic pain, as an adjunct therapy for partial seizures, and in generalized anxiety disorder. It was designed as a more potent successor to gabapentin. Pregabalin is marketed by  under the trade nam.

 

Pregabalin is used to relieve neuropathic pain (pain from damaged nerves) that can occur in your arms,

 hands, fingers, legs, feet, or toes if you have diabetes or in the area of your rash if you have had shingles (a painful rash that occurs after infection with herpes zoster). It is also used to treat fibromyalgia 

(a long-lasting condition that may cause pain, muscle stiffness and tenderness, tiredness, and difficulty falling 

asleep or staying asleep). Pregabalin is used with other medications to treat certain types of seizures in 

people with epilepsy. Pregabalin is in a class of medications called anticonvulsants. It works by decreasing the number of pain signals that are sent out by damaged nerves in the body.

 

3. Application:


Pregabalin is a white to off white, crystalline solid with a pKa1 of 4.2 and a pKa2 of 10.6. It is freely soluble in water and both basic and acidic aqueous solutions. The log of the partition coefficient (n-octanol/0.05M phosphate buffer) at pH 7.4 is 1.35.

LYRICA (pregabalin) Capsules are administered orally and are supplied as imprinted hard-shell capsules containing 25, 50, 75, 100, 150, 200, 225, and 300 mg of pregabalin, along with lactose 

monohydrate, cornstarch, and talc as inactive ingredients. The capsule shells contain gelatin and

 titanium dioxide. In addition, the orange capsule shells contain red iron oxide and the white capsule 

shells contain sodium lauryl sulfate and colloidal silicon dioxide. Colloidal silicon dioxide is a 

manufacturing aid that may or may not be present in the capsule shells. The imprinting ink contains

 shellac, black iron oxide, propylene glycol, and potassium hydroxide.

LYRICA (pregabalin) oral solution, 20 mg/mL, is administered orally and is supplied as a clear, colorless

 solution contained in a 16 fluid ounce white HDPE bottle with a Polyethylene lined closure. The oral solution contains 20 mg/mL of pregabalin, along with methylparaben, propylparaben, monobasic sodium phosphate anhydrous, dibasic sodium phosphate anhydrous, sucralose, artificial strawberry #11545 and purified water as inactive ingredients.

4. Pregabalin COA:

 

ITEMS STANDARDS RESULTS
Appearance A white to off white powder White powder
    Identification A. Meets the requirement Complies
B. IR: similar to Reference Substance Complies
Loss on drying ≤0.5% 0.21%
Specific Rotation +10.0°~+13.0° +10.8°
Related Substances Any single impurity ≤0.1%
Total impurity ≤0.8%
0.05%
0.10%
Purity By HPLC R-isomer ≤0.15% 0.10
Residue on ignition ≤0.1% 0.05%
Residual solvents Isopropyl alcohol ≤5000ppm
Ethyl Acetate   ≤5000ppm
150ppm
250ppm
Heavy metals ≤10ppm Complies
Chlorides ≤0.05% Complies
Assay 98%~102.0% 99.8%
Conclusion Analyse according to Factory Standard , Conform

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