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Anabolic Steroid Hormones Toremifene Citrate for Cancer Patients CAS 89778-27-8

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Anabolic Steroid Hormones Toremifene Citrate for Cancer Patients CAS 89778-27-8

China Anabolic Steroid Hormones Toremifene Citrate for Cancer Patients CAS 89778-27-8 supplier
Anabolic Steroid Hormones Toremifene Citrate for Cancer Patients CAS 89778-27-8 supplier Anabolic Steroid Hormones Toremifene Citrate for Cancer Patients CAS 89778-27-8 supplier

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Product Details:

Place of Origin: China
Brand Name: www.steroidaily.com
Certification: ISO9001
Model Number: 89778-27-8

Payment & Shipping Terms:

Minimum Order Quantity: 10g
Price: 1USD/G
Packaging Details: Special disguised packaging or as your demand
Delivery Time: within 24hours after confrim your payment
Payment Terms: Western Union, MoneyGram, T/T,Bitcoin
Supply Ability: plent of stock
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Detailed Product Description
CAS: 89778-27-8 Molecular Formula: C26H28ClNO C6H8O7
Molecular Weight: 598.09 Melting Point: 158-164 ° C
Boiling Point: 535.1° C At 760 MmHg Density: 1.045g/cm3
Appearance: White Or Almost White Powder Delivery: Within 24 Hours After Your Payment
Express: UPS,TNT,DHL.EMS,HKEMS,FEDEX Email: Service01@chembj.com

Anabolic Steroid Hormones Toremifene Citrate for Cancer Patients CAS 89778-27-8

 

 

Toremifene Citrate

 

Synonyms: (2-[4-((Z)-4-CHLORO-1,2-DIPHENYL-BUT-1-ENYL)-PHENOXY]-ETHYL)-DIMETHYL-AMINE;2-[4-(4-chloro-1,2-diphenyl-but-1-enyl)phenoxy]-n,n-dimethyl-ethanamine;TOREMIFENE;(z)-2-(4-(4-chloro-1,2-diphenyl-1-butenyl)phenoxy)-n,n-dimethylethanamine;2-(para-((z)-4-chloro-1,2-diphenyl-1-butenyl)phenoxy)-n,n-dimethylethylamine;2-diphenyl-1-butenyl)phenoxy)-n,n-dimethyl-2-(4-(4-chloro-(z)-ethanamin;(Z)-2-[4-(4-Chloro-1,2-diphenyl-1-butenyl)phenoxyl]-N,N-dimethylethylamine;C08166

CAS: 89778-26-7

Assay: 99%
Molecular Formula: C26H28ClNO. C6H8O7
Molecular Weight: 598.09
Melting Point: 158-164 º C
Boiling Point: 535.1 º C at 760 mmHg
Density: 1.045g/cm3
Refractive index: 1, 416-1, 418
Appearance: White or almost white powder
Usage: Originally developed to fight breast cancer, bodybuilders have used Fareston to successfully fight gynocomastia caused when testosterone converts to estrogen in the body and men grow breasts. This substance can be used for little else and other similar compounds, such as Nolvadex or Clomid, are much more effective in post-cycle-therapy.

 

Product Descriptions:

Toremifene Citrate is a Selective Estrogen Receptor Modulator derived from triphenylethelyne,it is used to treat breast cancer in post-menopausal women and Licensed in the United States under the brand name Fareston. It does this by exerting estrogen antagonistic effects in certain tissue,this is actually the same mechanism of action found in Nolvadex.Toremifene citrate is an oral selective estrogen receptor modulator (SERM) which helps oppose the actions of estrogen in the body,it has already been covered that Toremifene is a SERM, and serves to block Estrogen at various receptor sites in certain tissues within the body.At the hypothalamus and pituitary, estrogen acts in cooperation with the male body's negative feedback loop to send a signal to decrease the secretion of LH, and when LH secretion is lowered, so are natural testosterone levels.Fareston may act as an estrogen antagonist in the hypothalamus and pituitary, in order to increase testosterone production.

 

Toremifene Citrate improved lipid profiles, particularly as an enhancer of high density lipoprotein cholesterol. it improved low density lipoprotein cholesterol levels.Both fareston and tamoxifen selective estrogen receptor modulators and equivalent treatments for metastatic breast cancer.No significant differences were found between treatment with either tamoxifen or fareston Treatment of HR-positive patients with either tamoxifen or toremifene is appropriate.In treating idiopathic oligozoospermia, tamoxifen and fareston are roughly equally effective but raloxifene is not.The antiestrogenic effects of SERMs at the hypothalamic level result in a statistically significant increase of gonadotropin levels, which is more marked for tamoxifen and fareston compared with raloxifene.


Applications:


Toremifene citrate is an oral selective estrogen receptor modulator (SERM) which helps oppose the actions of estrogen in the body. Licensed in the United States under the brand name Fareston, toremifene citrate is FDA-approved for use in advanced (metastatic) breast cancer. It is also being evaluated for prevention of prostate cancer under the brand name Acapodene.


It has already been covered that Toremifene is a SERM, and serves to block Estrogen at various receptor sites in certain tissues within the body (breast tissue in particular). As a layman explanation, Toremifene pretends to be a 'fake' Estrogen that occupies Estrogen receptors within breast tissue. With these receptors occupied by Toremifene, real Estrogen cannot perform their jobs there. Toremifene does not reduce total blood plasma levels of Estrogen. In addition to being antagonistic to Estrogen receptors in breast tissue, it is also antagonistic to Estrogen at the hypothalamus gland (this essentially 'tricks' the hypothalamus into thinking there is little or no circulating Estrogen levels in the body, causing it to increase its manufacture of Testosterone so that it can utilize aromatization to restore these levels.
 

Toremifene is also agonistic to Estrogen receptors in other tissues in the body (within the liver in particular). This means that whileToremifene will act as an anti-estrogen in breast tissue and the hypothalamus, it will act as an Estrogen within the liver. This can have beneficial impacts especially during an anabolic steroid cycle, such as improving and shifting cholesterol levels into a more favorable range.

 

COA:

 


Tests

Specifications

Results

Appearance

White or off-white crystaline powder

White Crystalline powder

Solubility

Soluble in Chloroform;
Soluble in ethanol when heated

Conform

ldentification

Maximum absorption in
wavelength of 240 nm
Minimum absorption
in wavelength of 215 nm

Conform
Conform

Infrared spectrum should be
in accordance the dominant peak of contrast

In accordance with
the dominant peak of contrast

Melting points

182ºC-184ºC

182ºC

Related substances

≤0.5%

0.3%

Single impurity

≤0.3%

0.2%

Loss on drying

≤1.0%

0.8%

[Assay]C17H11N5
(On anhydrous basis)

≥98.0%

99.2%

Conclusion

Conforms Specifications of Enterprise Standard.

 

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Our advantage:

1.We have experience in exporting steroids, as you know, EU places much emphasis on them, and you must find a experienced partner who will assure you;
2.Quality:Our company is a professional leading factory in China in pharmaceutical area, We had stable customers and exported to Germany, Spain, UK, USA, Australia, Middle East, and any other countries.We can provide good references about our company.As for the quality of the products, we 're sure they can satisfy you well enough;
3.Package:Professional packing with professional materials
4.Delivery:We have products in stock, and we will deliver them soon when your PO arrived.Meanwhile we will give you the tracking number in order to make you know the exact location of the products.We will keep track of the product until they arrive you;We choose the best courier service for you, and with the delivery around 5-7 working days.
5.Service:Best Service with after-sales service and consultation

 

Anabolic Steroid Hormones Toremifene Citrate for Cancer Patients CAS 89778-27-8

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