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|Product Name:||GHRP-6||CAS NO.:||87616-84-0|
|Type:||Polypeptide Hormones||Grade:||Pharmaceutical Grade|
Growth Hormone Releasing Hexapeptide GHRP-6
Molecular formula: C46H56N12O6
Molar Mass: 873.014
CAS number: 87616-84-0
Purity (HPLC): 99.0%min.
Synonyms: Growth Hormone Releasing Peptide-6; GHRP6; GHRP 6
Appearance: Freeze Dried White Powder
Sterile Filtered White lyophilized (freeze-dried) powder.
The GHRP-6 peptide was lyophilized with no additives.
Hexapeptide (GHRP6) is one of several synthetic met-enkephalin analogs that include unnatural D-amino acids, were developed for their (GH) releasing activity and are called GH secretagogues. They lack opioid activity but are potent stimulators of GH release. These secretagogues are distinct from releasing hormone (GHRH) in that they share no sequence relation and derive their function through action at a completely different receptor. This receptor was originally called the GH secretagogue receptor, the hormone ghrelin is now considered the receptor' s natural endogenous ligand. Therefore, these GH secretagouges act as synthetic ghrelinmimetics.
Determining how efficient and the actions of the growth hormone is dependent on the physical condition of the experimental unit. For example, in humans, GH secretion decreases with obesity. On the other hand, GHRP-6, similar to Hexarelin, showed in one case increased (almost twice that of GHRP) GH responses when administered in obese patients (Cordido et al. 1993).
One side effect of GHRP-6 is a significant increase in appetite due to stimulating the release of Ghrelin, a peptide that is released naturally in the lining of the stomach that increases hunger and gastric emptying. Also, GHRP-6 causes stimulation of the anterior pituitary gland which causes an increase in Growth Hormone release. The increased amounts of Growth Hormone can cause the liver to secrete the hormone IGF-1, which improves the animal body’s ability to burn fat and build muscle. Since GHRP-6 acts directly on the feedback loop which signals the inhibition of Growth Hormone release, GHRP-6 can re-stimulate the production of Growth Hormone.
|Column||Sinochrom ODS-BP, 4.6*250mm, 5um|
|Solvent A||0.1%Trifluoroacetic in 100% Acetonitrile|
|Solvent B||0.1%Trifluoroacetic in 100% Water|
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