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|Name:||Tetracaine Hydrochloride||Alias:||Tetracaine HCl|
Product name: Tetracaine hydrochloride
Other name: Tetracaine HCL; Amethocaine hydrochloride; Pontocaine HCl
Chemical names: L and ocain hydrochloride; Intercain hydrochloride; Meethobalm hydrochloride; 2-(dimethylamino)ethyl 4-(n-butylamino)benzoate hydrochloride; 2-dimethylaminoethyl ester ofp-butylaminobenzoic acid hydrochloride; 4-(n-butylamino)benzoic acid 2-(dimethylamino)ethyl ester hydrochloride; 4-[butylamino]benzoic acid-2-[dimethylamino]ethyl ester hydrochloride; 4-butylaminobenzoic acid dimethylaminoethyl ester HCl
CAS number: 136-47-0
Molecular formula: C15h25cln2o2
Molecular weight: 300.82
Appearance: White crystalline powder, Tetracaine hydrochloride is 2-(Dimethylamino)ethyl p-(butylamino)benzoate monohydrochloride. It is a white crystalline, odorless powder that is readily soluble in water, physiologic saline solution, and dextrose solution.
Usage: Tetracaine hydrochloride has been used for studying the pharmacological effects of spinal anesthesia. A crystalline compound related to procaine and used as a local anesthetic.
Keywords: Tetracaine Hydrochloride, Tetracaine Hyc, Tetracaine HCl for Sell, Buy Tetracaine, Local Anesthetics, Local Anaesthetic Lidocaine, Benzocaine, Procaine, Procaine Hydrochloride, Tetracaine Hydrochloride Powder, Tetracaine HCl Topical
Tetracaine is a local anesthetic (numbing medicine). It works by blocking nerve signals in your body.Tetracaine injection is given as an epidural injection into the spinal column to produce numbness during labor, surgery, or certain medical procedures.Tetracaine may also be used for purposes not listed in this medication guide.
Tetracaine hydrochloride is indicated for the production of spinal anesthesia for procedures requiring two to three hours. Parenteral administration of Tetracaine hydrochloride stabilizes the neuronal membrane and prevents initiation and transmission of nerve impulses thereby effecting local anesthesia.
The onset of action is rapid, and the duration is prolonged (up to two or three hours or longer of surgical anesthesia).Tetracaine hydrochloride is detoxified by plasma esterases to aminobenzoic acid and diethylaminoethanol.
|Extent of||Dose of solution||Volume of spinal fluid||Site of injection|
|Perineum||0.5 (= 5 mg)*||0.5||4th|
|Perineum and||1.0 (= 10 mg)||1.0||3rd or 4th|
|Up to costal||1.5 to 2.0||1.5 to 2.0||2nd, 3rd, or 4th|
|margin(= 15 mg to 20 mg)?|
1. For tonometry and other short procedures: Instill 1 to 2 drops in the eye(s) just prior to evaluation.
2. For minor surgical procedures, such as foreign body or suture removal: Instill 1 to 2 drops in the eye(s) every 5 to 10 minutes for 1 to 3 instillations.
3. For prolonged anesthesia, such as cataract extraction: Instill 1 to 2 drops in the eye(s) every 5 to 10 minutes for 3 to 5 doses.
|Test Items||Specification||Test Results|
|Appearance||Fine, white, crystalline, odorless powder||confirm|
|Identification||ABC in Pass||confirm|
|Solubility||Very soluble in water, soluble in Alcohol; insoluble in Ether and Benzene||confirm|
|USP Reference standards||USP Tetracaine Hydrochloride RS. USP Endotoxin RS.||confirm|
|Melting point||145~150 degree||146.0~147.5
|Chromatographic purity||In Pass||confirm|
|Related substance||Not more than the reference solution 0.05%||confirm|
|Residue on ignition||≤0.10%||0.05%|
|Loss on Drying||≤ 0.5%||0.19%|
|Conclusion||Confirms USP 32|
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