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Paracetamol its antipyretic and analgesic effects and aspirin similar, but antiphlogistic fights rheumatism role is very weak, the little sense. For gastrointestinal non-irritating, it doesn't cause coagulation disorders is its advantages.
Paracetamol is a painkiller for mild to moderate pain. It can also control high temperatures (fever). It has a number of different brand names – for example Panadol, Anadin and Calpol. Paracetamol may be contained in other medicines such as Anadin Extra and cold remedies like Beechams and Benylin. In America it is also known as acetaminophen or Tylenol.
Paracetamol is approved for reducing fever in people of all ages.
Paracetamol is used for the relief of pains associated with many parts of the body. It has analgesic properties comparable to those of aspirin, while its antiinflammatory effects are weaker. It is better tolerated than aspirin in patients in whom excessive gastric acid secretion or prolongation of bleeding time may be a concern.
The product is antipyretic analgesics, international non-proprietary drug called Paracetamol. It is the most common non-inflammatory and antipyretic analgesic, antipyretic effects of aspirin and similar analgesic effect is weak, no anti-inflammatory anti-rheumatic effects acetanilide drugs is the best varieties. Particularly suitable for patients can not be applied to acid-based drugs. For colds, toothache embolism. Acetaminophen is the organic synthesis intermediates, hydrogen peroxide stabilizers, photographic chemicals.
|Appearance||White or almost white ,crystalline powder.||White,crystalline powder.|
|Water||Not more than0.5%||0.08%|
|Related substance||Impurity(chloroacetanilide)not more than 10 ppm||2ppm|
|Impurity K(4-aminophenol)not more than 50 ppm||15 ppm|
|Impurity F(4-nitrophenol)not more than 0.05%||Not detected|
|any other impurity not more than 0.05%||0.01%|
|Total of other impurities not more than 0.1%||0.02%|
|Residue on ignition||Not more than 0.1%||0.05%|
|Chloride||Not more than 0.014%||Less than 0.014%|
|Sulfate||Not more than 0.02%||Less than 0.02%|
|Heavy metals||Not more than 0.001%||Less than 0.001%|
|Free p-aminophenol||Not more than 0.005%||Less than 0.005%|
|Limit of P-chloroacetanilide||Not more than 0.001%||Less than 0.001%|
|Readily carbonizable substances||Conforms||Conforms|
|Residual solvents||Residual content of acetic acid is limited by the test of loss on dryingnot more than0.5%||0.08%|
|Conclusion: Complies with USP34/ BP2011|
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