Pharmaceutical Raws Propranolol Hydrochloride CAS 318-98-9 for Antianginal Usage

Pharmaceutical Raws Propranolol Hydrochloride CAS 318-98-9 for Antianginal Usage

Product Name: Propranolol hydrochloride
Synonyms: (RS)-1-[(1-METHYLETHYL)AMINO]-3-(1-NAPHTHALENYLOXY)-2-PROPANOL HYDROCHLORIDE;PROPRANOLOL HCL;(+/-)-PROPRANOLOL HYDROCHLORIDE;PROPRANOLOL HYDROCHLORIDE;(+/-)-PROPANOLOL HCL;PROPANOLOL HYDROCHLORIDE;1-((1-methylethyl)amino)-3-(1-naphthalenyloxy)-2-propanohydrochloride;1-(1-naphthyloxy)-2-hydroxy-3-isopropylaminopropanehydrochloride
CAS: 318-98-9
MF: C16H22ClNO2
MW: 295.8
EINECS: 206-268-7

Propranolol hydrochloride Usage And Synthesis

Chemical Properties Off-White to Light-Yellow Cyrstalline Solid
Usage β?Adrenergic blocker. Antihypertensive; antianginal; antiarrhythmic (class II).
Usage For the prophylaxis of migraine

Propranolol  Medical uses

An 80 mg capsule of extended-release propranolol

A mixture of 20 mg and 10 mg propranolol tablets
Propranolol is used for treating various conditions, including:

Cardiovascular[edit]
Hypertension
Angina pectoris (with the exception of variant angina)
Tachyarrhythmia
Myocardial infarction
Tachycardia (and other sympathetic nervous system symptoms, such as muscle tremor) associated with various conditions, including anxiety, panic, hyperthyroidism, and lithium therapy
Portal hypertension, to lower portal vein pressure
Prevention of esophageal variceal bleeding and ascites
Anxiety
Asymmetric septal hypertrophy
While once a first-line treatment for hypertension, the role for beta blockers was downgraded in June 2006 in the United Kingdom to fourth-line, as they do not perform as well as other drugs, particularly in the elderly, and evidence is increasing that the most frequently used beta blockers at usual doses carry an unacceptable risk of provoking type 2 diabetes.[11]

Propranolol is not recommended for the treatment of hypertension by the Eighth Joint National Committee (JNC 8) because a higher rate of the primary composite outcome of cardiovascular death, myocardial infarction, or stroke compared to an angiotensin receptor blocker was noted in one study.[12]