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Intermediates Powder Etoricoxib CAS 202409-33-4 for Antiinflammatory

Intermediates Powder Etoricoxib CAS 202409-33-4 for Antiinflammatory

  • Intermediates Powder Etoricoxib CAS 202409-33-4 for Antiinflammatory
  • Intermediates Powder Etoricoxib CAS 202409-33-4 for Antiinflammatory
  • Intermediates Powder Etoricoxib CAS 202409-33-4 for Antiinflammatory
Intermediates Powder Etoricoxib CAS 202409-33-4 for Antiinflammatory
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Place of Origin: China
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Detailed Product Description
CAS: 202409-33-4 MF: C18H15ClN2O2S
MW: 358.84 Source: Synthetic
Purity: 99%min. Properties: Powder
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Delivery Mode: EXPRESS Door To Door
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Intermediates Powder Etoricoxib CAS 202409-33-4 for Antiinflammatory


Product Name: Etoricoxib
Synonyms: 5-chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfonylphenyl)pyridine;ETORICOXIB;5-Chloro-6'-methyl-3-[4-(methylsulfonyl) phenyl]-2,3'-bipyridine;Arcoxia;5-chloro-3-(4-Methanesulfonylphenyl)-2-(6-Methylpyridin-3-yl)pyridine;Etoricoxib-D4;2,3'-Bipyridine, 5-chloro-6'-Methyl-3-[4-(Methylsulfonyl)phenyl]-;Algix
CAS: 202409-33-4
MF: C18H15ClN2O2S
MW: 358.84


Etoricoxib Pharmacological effects


Etoricoxib is a non-steroidal anti-inflammatory drug with anti-inflammatory, analgesic and antipyretic effects in animal models. It is a kind of orally active, selective cyclooxygenase-2 inhibitor within the clinical dose range or higher doses. It has already confirmed of two subtypes of cyclooxygenase: cyclooxygenase -1 (COX-1) and cyclooxygenase -2 (COX-2). COX-1 is involved in the prostaglandin mediated normal physiologic functions such as gastric cytoprotection and platelet aggregation. Non-selective non-steroidal anti-inflammatory drugs inhibit the generation of COX-1, and thus can cause gastric mucosal injury and decreased platelet aggregation. COX-2 is mainly involved in the production of prostaglandins, and prostaglandins can cause pain, inflammation and fever. Etoricoxib is a kind of selective COX-2 inhibitors which can reduce these symptoms and signs as well as reduce gastrointestinal side effects without affecting platelet function.


Etoricoxib Usage And Synthesis


Chemical Properties Off-White Powder
Usage A specific inhibitor of COX-2 .
Usage anti-inflammatory, analgesic;cyclooxygenase inhibitor
Usage For the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout.
Usage Labeled Etoricoxib, intended for use as an internal standard for the quantification of Etoricoxib by GC- or LC-mass spectrometry.


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