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| Place of Origin: | China |
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| Certification: | Enterprise Standard |
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| Minimum Order Quantity: | 1G |
|---|---|
| Price: | USD1 |
| Packaging Details: | Disguised Package |
| Delivery Time: | Within 24 hours |
| Payment Terms: | T/T, , |
| Supply Ability: | 50000000 |
| CAS: | 74150-27-9 | MF: | C19H18N4O2 |
|---|---|---|---|
| MW: | 334.37 | Source: | Synthetic |
| Purity: | 99%min. | Properties: | Powder |
| Payment: | T/T, , , Bitcoin | Delivery Time: | Within 24 Hours |
| Delivery Mode: | EXPRESS Door To Door | ||
| High Light: | pharma raw materials,medicine raw material |
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Pharmaceuticals Pimobendan CAS 74150-27-9 for Antiviral Usage
Product Name: Pimobendan
Synonyms: PIMOBENDAN;4,5-dihydro-6-[2-(4-methoxyphenyl)-1h-benzimidazol-5-yl]-5-methyl-3(2h)-pyridazinone;PIMOBENDANE HCL;Pimobendam;3(2H)-Pyridazinone, 4,5-dihydro-6-2-(4-methoxyphenyl)-1H-benzimidazol-5-yl-5-methyl-;3(2H)-Pyridazinone, 4,5-dihydro-6-[2-(4-methoxyphenyl)-1H-benzimidazol-5-yl]-5-methyl- (9CI);dl-Pimobendan;Racemic pimobendan
CAS: 74150-27-9
MF: C19H18N4O2
MW: 334.37
Pimobendan Usage And Synthesis
Chemical Properties White Solid
Usage antiviral
Usage Pimobendan is a cardiotonic agent. The study of the cardiotonic mechanism of Pimobendan using ventricular muscles from rabbits and guinea pigs suggests that Pimobendan acts by inhibiting phosphodiesterase III and potassium channel. The potent venodilating action of Pimobendan makes it a suitable treatment option for patients with congestive heart failure (CHF) as it also improves systemic vasoconstriction.
Usage Pimobendan is a selective inhibitor of PDE3 with IC50 of 0.32 μM
Pimobendan Combinations
Pimobendan is often used in combination with three other drugs to palliate dogs with heart failure (pulmonary edema, pleural effusion, ascites). These are:
Furosemide, a diuretic, to reduce edema and effusion.
Spironolactone, an aldosterone antagonist. This has two actions, firstly, as a potassium-sparing diuretic, although its diuretic properties are small compared with those of furosemide. Secondly, it reduces aldosterone-mediated myocardial fibrosis, possibly slowing the progression of heart disease.
An ACE inhibitor, often enalapril (trade name Enacard) or benazepril (Fortekor). These drugs inhibit the action of angiotensin-converting enzyme, producing a balanced vasodilation, along with other potentially favorable effects.
Other drugs may also be used as required to manage certain arrhythmias that are often associated with heart disease.
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