Steroid Powders Hydroxyprogesterone / 17-Hydroxy Progesterone CAS 68-96-2

Steroid Powders Hydroxyprogesterone / 17-Hydroxy Progesterone CAS 68-96-2

Hydroxyprogesterone
Product Name: Hydroxyprogesterone
Synonyms:    17-Hydroxypregn-4-en-3,20-dione;17-hydroxy-pregn-4-ene-20-dione;17-hydroxypregn-4-ene-3,20-dione;delta(4)-pregnene-17alpha-ol-3,20-dione;gestagenogador;prodix;prodox;(8R,9S,10R,13S,14S,17R)-17-ACETYL-17-HYDROXY-10,13-DIMETHYL-1,2,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE
CAS:    68-96-2
MF:    C21H30O3
MW:    330.46
EINECS: 200-699-4
Chemical Properties    White Solid
Usage    Progesteron. It was isolated from adrenal glands.
Usage    anticoagulant
Usage    17α-Hydroxy Progesterone is a metabolite of Progesterone. It was isolated from adrenal glands.

Hydroxyprogesterone Applications:

The 17-hydroxyprogesterone (17-OHP) test is routinely ordered as part of newborn screening in the UnitedStates to detect congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency. CAH is a group ofinherited disorders caused by specific gene mutations and associated with cortisol-related enzymedeficiencies. About 90% of CAH cases are caused by a mutation in the 21-hydroxylase gene (also calledP450c1 or CYP21A2) and may be detected due to the accumulation of 17-OHP in the blood.
The 17-OHP test may be used to screen for CAH in older children or adults before symptoms appear or toconfirm a CAH diagnosis in people with symptoms.