 |
| Place of Origin: | china manufactuer |
| Brand Name: | steriodshow |
| Certification: | Enterprise Standard |
| Model Number: | ycwlb045@yccreate.com |
| Minimum Order Quantity: | 10g |
|---|---|
| Price: | USD1 |
| Packaging Details: | Special disguised packaging or as your demand |
| Delivery Time: | within 12hours after payment |
| Payment Terms: | T/T, , |
| Supply Ability: | plent of stock |
| CAS: | 136-47-0 | MF: | C15H25ClN2O2 |
|---|---|---|---|
| MW: | 300.82 | EINECS: | 205-248-5 |
| Purity: | 99%min. | Properties: | Powder |
| Payment: | T/T, , , Bitcoin | Delivery Time: | Within 24 Hours |
| Delivery Mode: | EXPRESS Door To Door | ||
| High Light: | topical local anesthetic,medicine raw material |
||
Local Anesthetic Drugs Tetracaine Hydrochloride / Tetracaine HCL CAS 136-47-0
Tetracaine hydrochloride
Product Name: Tetracaine hydrochloride
Synonyms: L AND OCAIN HYDROCHLORIDE;INTERCAIN HYDROCHLORIDE;MEETHOBALM HYDROCHLORIDE;2-(DIMETHYLAMINO)ETHYL 4-(N-BUTYLAMINO)BENZOATE HYDROCHLORIDE;2-DIMETHYLAMINOETHYL ESTER OFP-BUTYLAMINOBENZOIC ACID HYDROCHLORIDE;4-(N-BUTYLAMINO)BENZOIC ACID 2-(DIMETHYLAMINO)ETHYL ESTER HYDROCHLORIDE;4-[BUTYLAMINO]BENZOIC ACID-2-[DIMETHYLAMINO]ETHYL ESTER HYDROCHLORIDE;4-BUTYLAMINOBENZOIC ACID DIMETHYLAMINOETHYL ESTER HCL
CAS: 136-47-0
MF: C15H25ClN2O2
MW: 300.82
EINECS: 205-248-5
Chemical Properties White Solid
Usage anesthetic (local)
Usage A local anesthetic used topically in opthalmology.
Tetracaine hydrochloride Description:
Tetracaine HCl is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.
Tetracaine hydrochloride Application:
Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.
In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.
use:Used for mucosal epidermal anesthesia, nerve tissue anesthesia, epidural anesthesia and Subarachnoid space anesthesia.
In the manufacture of pharmaceutical preparation for external use, to relieve the pain of drugs or medication lesions pain.
Tetracaine hydrochloride Specification:
|
Items |
QUALITY STANDARDS |
RESULTS |
|
Description |
White or almost white crystalline powder |
White crystalline powder |
|
Solubility |
Matching with the working standard |
Complies |
|
Identification |
A.By IR, To match with working standard |
Complies |
|
B: To 10ml of solution S add 1ml of ammonium thiocyanate solution R.A white,crystalline precipitate is formed which,after recrystallisation from water R and drying at 80℃ for 2h,melts at about 131℃ |
Complies |
|
|
C. To about 5mg add 0.5ml of fuming nitric acid R .Evaporate to dryness on a water-bath,allow to cool and dissolve the residue in 5ml of acetone R.Add 1ml of 0.1M alcoholic potassium hydroxide.A violet colour develops |
Complies |
|
|
|
D. Solution S gives reaction of chlorides. |
Complies |
|
PH |
4.5～6.5 |
5.78 |
|
Residual Solvents |
Conform to standard |
Complies |
|
Claruty |
Solution should be clear |
Complies |
|
Related Substances |
Conform to standard |
Complies |
|
Heavy metals |
≤10ppm |
＜10ppm |
|
Loss on drying |
≤1.0% |
0.87% |
|
Resiue on ignition |
≤0.1% |
0.05% |
|
Melting range |
148℃ |
147.5℃～150.8℃ |
|
Assay(*) |
99%～101.0% |
100.40% |
|
Conclusion |
The Sample Complies With Specification of EP8 |
|
| Propitocaine hydrochloride | CAS: 1786-81-8 |
| Tetracaine hydrochloride | CAS: 136-47-0 |
| Procaine hydrochloride | CAS: 51-05-8 |
| Pramoxine hydrochloride | CAS: 637-58-1 |
| Proparacaine hydrochloride | CAS: 5875-06-9 |
| Benzocaine hydrochloride | CAS: 23239-88-5 |
| Lidocaine hydrochloride | CAS: 73-78-9 |
| Articaine hydrochloride | CAS: 23964-57-0 |
| Levobupivacaine hydrochloride | CAS: 27262-48-2 |
| Ropivacaine hydrochloride | CAS: 132112-35-7 |
| Dibucaine hydrochloride | CAS: 61-12-1 |
| Bupivacaine hydrochloride | CAS: 14252-80-3 |
| Articaine | CAS: 23964-58-1 |
| Benzocaine | CAS: 94-09-7 |
| Lidocaine | CAS: 137-58-6 |
| Tetracaine | CAS: 94-24-6 |
| PROCAINE | CAS: 59-46-1 |
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