Raw Steroid Powders Estradiol CAS 50-28-2 for Estrogenic Hormone

Raw Steroid Powders Estradiol CAS 50-28-2 Estrogenic Hormone Powder

Estradiol

Product Name: Estradiol 
Synonyms: BETA-ESTRADIOL-16,16,17-D3;17BETA-ESTRADIOL-16,16,17-D3;(+)-3,17β-estradiol;(17b)-estra-1,3,5(10)-triene-3,17diol;(17β)-estra-1,3,5(10)-triene-3,17diol;.alpha.-Oestradiol;.beta.-Oestradiol;17-.beta.-Estra-1,3,5(10)-triene-3,17-diol 
CAS: 50-28-2 
MF: C18H24O2 
MW: 272.38 
EINECS: 200-023-8 

Chemical Properties White Crystalline Powder 
Usage Potent mammalian estrogenic hormone produced by the ovary. 
Usage Estradiol is the major estrogen secreted by the premenopausal ovary. 
Biological Activity Endogenous estrogen receptor (ER) agonist (K i values are 0.12 and 0.13 nM for ER α and ER β respectively). Also high affinity ligand at membrane estrogen GPR30 receptors. 

Estradiol details:

Estrogen drugs. Used for functional uterine bleeding, primary amenorrhea, menopause syndrome, prostate cancer. To promote and regulate women's genitals and secondary normal development. Can cause hyperplasia of mammary gland carcinoma development, but in larger doses, can inhibit pituitary prolactin release, and reduce the secretion of milk. Can also be used for milk. But there may be nausea, vomiting and endometrial hyperplasia of excessive bleeding, etc. Liver and renal insufficiency with caution. Avoid is used for breast, vulva and vaginal mucosa.
Estradiol (o) estradiol C18H24O2 being a sex hormone. With alpha, beta, two types of alpha physiological function is strong. Steiner, winter (Wintersteiner et al. 1935) was extracted from the horse urine pregnancy, moreover also can cause from the urine, placenta, pig ovary, etc. There is also a male horse testis or urine. Because it has the very strong sex role, so that it or its ester is, in fact, ovarian secretion of the sex hormones of the most important. Estradiol benzoate is decided to one of the international unit of sex hormone titer standard substance and used.

Estradiol Function:

Function and use: It is a kind of estrogen, can promote and regulate the normal development of women's genitals and secondary. Can cause hyperplasia of mammary gland carcinoma development, but in larger doses, can inhibit pituitary prolactin release, and reduce the secretion of milk. Potent mammalian estrogenic hormone produced by the ovary.