Estrogen Agonist Raloxifene Hydrochloride light yellow powder Pharmaceutical raw material CAS 82640-04-8

1. Description:
 
Raloxifene hydrochlorideis an estrogen agonist/antagonist, commonly referred to as a selective estrogen receptor modulator (SERM) that belongs to the benzothiophene class of compounds. Raloxifene hydrochloride (HCl) has the empirical formula C28H27NO4SHCl, which corresponds to a molecular weight of 510.05. Raloxifene HCl is an off-white to pale yellow solid that is very slightly soluble in water.
 
2. Quick details:
Product name: Raloxifene hydrochloride 
CAS :  82640-04-8
Molecular Formula: C28H28ClNO4S
Molecular Weight: 473.58328
Melting point: 143-147degree  centigrade
Boiling Point: 728.2 degree centigrade at 760 mmHg
Flash Point: 394.2 degree  centigrade
Density:1.285 g/cm3
Water solubility:DMSO: 28 mg/mL, soluble
Appearance: Light yellow solid
Indications: This product is mainly used to prevent postmenopausal osteoporosis
Usage of Raloxifene Hydrochloride : Used for the prevention and treatment of postmenopausal osteoporosis, can significantly reduce the incidence of vertebral fractures.
3. Additional Info: 
Synonyms:Raloxifene HCl
Assay:99%
Delivery Time:Within 24 Hours After Payment
Shipping:Express Courier(EMS, DHL, UPS, TNT, FedEx)
Export Markets:Global
Trademark:shuangbojie
Packing:Disguised Package or as Required
Origin:China
HS Code:29144000
Storage: Stored in cool and dry place, keep away from strong light /heat.
Shelf Life: 2 years when properly stored.​
 
4. Application:
 
Breast Cancer
Reduction in the incidence of invasive breast cancer in postmenopausal women with osteoporosis.
Reduction in the incidence of invasive breast cancer in postmenopausal women at high risk for developing the disease. Effect comparable to that of tamoxifen in reducing the risk of invasive breast cancer (STAR trial). No effect on the risk of lobular carcinoma in situ or ductal carcinoma in situ (STAR trial). Effect on breast cancer incidence in women with BRCA1 or BRCA2 genetic mutations not established.
 
5. Function of Cyproterone:

• Used in the treatment of male sexual desire is unusual, women hirsutism, acne, precocious puberty and prostate cancer, etc.
• Has function of resistant sexual desire to a variety of sexual perversion (gay, exhibitionism, voyeurism, pedophiles) and heterosexual hypersexuality.
• This product and ethinylestradiol compound, can be used as a short-acting oral contraceptives.Also has the obvious curative effect for female acne.
• For women Contraception Is a kind of high efficiency, low toxicity and no side effects of a new generation of nonsteroidal pill;
• With resistance to salt cortex hormone and antiandrogen role, has a broad market prospect.

6  COA: