Polypeptide Hormones Melanotan I Human Growth Hormone MT-1 Melanotan 1 for medical use

Polypeptide Hormones Melanotan I Human Growth Hormone MT-1 Melanotan 1 for medical use

1.  Quick Detail:
 

MT 1 Model No.: Melanotan I 10mg/vial, 100vial/kit
Melanotan Export Markets: Global
Melanotan I  Product Description
Melanotan I
CAS: 75921-69-6
Formula: C78H111N21O19
Chain: AC-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-PRO-Val-NH2
Appearance: Sterile Filtered White lyophilized (freeze-dried) powder
Purity(by HPLC): >99.00%~99.90%
Total Impurities(by HPLC): 1.00%~0.05%
Single Impurity(by HPLC): <0.50%~0.08%
Origin: China (Mainland)
Storage conditions: Aviod shunshine and keeping stoppered

2.  Description:

MT-1 (or Melanotan I, or Afamelanotide, or CUV-1647) 

is a synthetic analog of peptides nature of endogenous melanocortine peptide alpha-melanocyte 

stimulating hormone. It has hormones nature as well as common proteins features, its molecular 

weight/mass is 1646.88 and its molecular formula is C78H111N21O19.

Melanotan-1 Mechanism of Action - How it Works!
Melanotan produces its photoprotective effects by triggering a 'signaling cascade' via its activation of the MC1R on melanin-producing cells known as melanocytes. Upon Melanotan binding with the MC1R on the surface of melanocytes in the epidermal layer of the skin, it begins a series of actions and reactions that result in melanocytes favoring the production of eumelanin (photoprotective black/brown pigment). The initial binding activates the MC1R leading to the activation of adenylate cyclase (AC) and stimulation of the production of cyclic adenosine monophosphate (cAMP). cAMP in turn activates protein kinase A (PKA) resulting in the phosphorylation of the cAMP response element-binding (CREB). Phosphorylated CREB will bind to the cAMP response element (CRE) on the microphthalmia-associated transcription factor (MITF) gene leading to the synthesis of the MITF protein. MITF has the ability to activate several genes by binding to them, including the MC1R gene and the genes involved in melanogenesis. This results in increased concentrations of the melanogenic enzymes within the melanocyte.

Product Picture:

3.  Applications:

Start with a dose of 1mg daily for the first two or three days and, if level of side effects permit, look to 

increase dosage by 0.25mg every day over the next several days until you reach a daily dosage of 

2-3mg. This level should be adequate for most users, though some may wish to increase yet further, 

perhaps as high as 5mg daily in order to achieve a very deep tan. A maintenance phase as described 

above is then used.

Melanotan 1 (also referred to as Afamelanotide) is a synthetic peptide variant of a peptide hormone, called alpha-Melanocyte stimulating hormone or MSH that is naturally produced in the body and is responsible for stimulating melanogenesis, a peptide process for pigmentation of the skin. Alpha-

MSH activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH

also exerts potent influence over lipid metabolism, appetite, and sexual libido via these melanocortin receptors. As a result, Melanotan-1 sunless skin tanning effects. While Melanotan 2 and PT-141

have been studied at length as a potential remedies for the treatment of sexual dysfunction,

Melanotan-has been researched extensively for use in protecting against the harmful effects of

ultraviolet radiation from sunlight due to its melanogenesis-stimulating properties. 

Administration
Both MT and MT II are currently supplied as white lyophilised powder contained in a sealed multi-use

vial. The peptide is susceptible to temperature degradation and should be shipped preferably with an

ice pack though contrary to popular belief, the rate of degradation is very slow (weeks) in its powder

form, so there's no need to be alarmed if yours wasn't shipped in this manner or you are unable to

collect your package from a depot for a day or two. Once delivered, the powder is best stored in a freezer, or refrigerated if this is not possible.
To prepare for injection, it must be reconstituted with bacteriostatic water. You may use anything

between 1ml and 5ml of water for your vial. Dependant upon the amount of water used will determine

the concentration of your solution. For example, a 10mg vial of Melanotan II mixed with 1ml of water will provide a solution of 10mg per 1ml (10mg/ml). This means that a 1mg dose will require a shot of 0.1ml. Bearing in mind that the recommended starting dose is 0.25mg, using the example above, the actual volume of the shot would be 0.025ml (¼ of 1 tenth of a ml). This is a very small volume and very

difficult to accurately dose even with a 0.5ml insulin syringe. Therefore, at least until your dosages

have increased, it is suggested that you use more water for your vial.
An example of a good solution would be to mix 10mg of Melanotan II powder with 4ml of bacteriostatic water. This now provides:
10mg/4ml or 1mg/0.4ml or 0.25mg/0.1ml
0.1ml can be accurately measured using a 0.5ml or 1ml syringe.
Obviously, as your dosages become higher, you may dilute subsequent vials with lower amounts of

water to reduce the volume of each shot. I would recommend that when you are using a dosage of

1mg, you reconstitute the vial with 1ml or 2ml of water so that each shot will be 0.1ml or 0.2ml respectively.

Specification: 10mg/vial, 10vial/box

Polypeptide Hormones we supply

Competitive Advantages:
 
Hello,Zhuhaishi Shuangbojie Technology Co.,ltd is a leading worldwide professional manufacture of 
medications.We supply hundreds of different types of medications including testosterone,trenbolone, 
nandrolone, ect.We ship through EMS with tracking numbers.  
1. Rich experience.
We only send the HIGHEST purity Steroids, Peptides, Research chemicals & Pharmaceuticals which 
are very popular in many countries.Our steroids and hormones have been exported to overseas, like 
USA, Canada,UK,Brazil,Netherlands, Ireland, New Zealand, Austria, Australia and so on.And we have 
got very good feedback from our customers, and established long friendly relations of cooperation.
2,Best price
Our prices are the best because of the discounts that we give to all our buyers. We give very good 
discounts which makes our prices outstanding in the market.
2. Great quality, purity and favorable.
Genuine and 100% Guarantee on all orders you place. We Have the Best you will come across Online. 
We, As well Provide Tracking on Packages as they are being sent.Our MOQ is 10grams,any trial order 
is welcome,you can make decisions of committing to buying in bulk once our product has been tested.
3 Experiential shopping
Besides raw steroid powder and liquid, we offer hormone solution and formula. We can teach you how 
to make hormone solution on the site. Any visit to our lab is welcomed.
4 Good after-sales service.
We will always send you top quality products with very competitive price,we as well offer best customer 
service and excellent shipment ability,i wish you can email me and let me introduce my products for you.