Polypeptide GHRP-2 Acetate Growth Hormone Release Peptide-2 GHRP-2 for Muscle Gaining

Polypeptide GHRP-2 Acetate Growth Hormone Release Peptide-2 GHRP-2  for Muscle Gaining

1.  Quick Detail:
 

Unit Size :5 mg/vial 
Unit Quantity :1 Vial 
CAS NO. :158861-67-7 
Synonyms :GHRP-2 Acetate 
Molecular Formula :C45H55N9O6 
Molecular Weight :817.97 
Sequence :H-D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2 
Appearance :White Powder 
Purity :99.35% 
Identity (ESI-MS) :817.97±1.0 
Source :Chemical Synthesis 
Storage :Lyophilized GHRP-2 is stable at room temperature for 90 days,however it should be stored in a freezer below -8C for any 

extended period of time. After reconstituting GHRP 2 should be refrigerated at temperatures not to 

exceed 36 F. 

Specification:10mg/vial*10vial/kit,5mg/vial*10vial/kit

2.  Description:

What is the GHRP-2 ?
GHRP-2 is a synthetic agonist of ghrelin, the newly-discovered gut peptide which binds to the (GH) secretagogue receptor. Ghrelin has two major effects, stimulating both GH secretion and appetite/

meal initiation. GHRP-2 has been extensively studied for its utility as a secretagogue (GHS). Animal studies have shown its effect on food intake. However, whether GHRP-2 can also stimulate appetite

in humans when administered acutely is not known. We subcutaneously infused 7 lean, healthy males with GHRP-2 (1 microg/kg/h) or saline for 270 minutes and then measured their intake of an ad libitum, buffet-style meal. These data are the first to demonstrate that GHRP-2, like ghrelin, increases food intake, suggesting that GHRP-2 is a valuable tool for investigating ghrelin effects on eating behavior

in humans.

GHRP-2 and Ipamorelin are all very similar in their modes of action, they work to increase 

Growth Hormone (GH) levels in the human body by increasing secretion of the hormone Ghrelin. 

On a milligram for milligram basis they are all fairly equal in their ability to increase GH 

levels in the human body, with GHRP-2 being slightly more efficient.The major 

differences between the 3 GHRP peptides lays in their side effects. GHRP-6 causes a significant 

increase in hunger for many, therefore making it good for people looking to "bulk" but no so 

good for those trying to lose fat. GHRP-2 is often preferred for people dieting as it does not 

stimulate hunger, however it does raise cortisol (a stress hormone), prolactin (a hormone which 

can diminish sex drive) and aldosterone (a hormone which promotes water retention) more 

than GHRP-6 and Ipamorelin. Ipamorelin is similar to GHRP-6 in that it causes an increase in 

hunger (but it's not as dramatic as GHRP-6). However, since it does not raise cortisol, prolactin or 

aldosterone at recommended dosages it is a preferred choice for those who are sensitive to

these hormones.

Product Picture:

3.  Applications:

GHRP-2 is a 2nd generation GHRP just behind GHRP-6. Compared to GHRP-6, GHRP-2 is 

considered to be much more superior in terms of growth hormone stimulation because over longer 

periods of time it maintains maximum elevations in Growth Hormone. GHRP-2 has shown 

to increase IGF-1 levels (Insulinlike Growth Factor 1), and even greater results happen when 

used with Growth Hormone Releasing Hormone (GHRH). It has a short half life withpeak 

concentrations occurring around 15 minutes but not longer than 60 minutes. The response of 

natural physiologic system includes increase in levels of calcium ion influx alongside with increased 

release of growth hormones in response to the high-amplitude pulsation from the GHRP-2. GHRP-2 

and other ghrelin analogues increase the number of somatotropes involved in the GH pulse by 

inhibiting somatostatin, GHRH increases the pulse amplitude per pituitary cell or somatotrope by 

other means. Unlike ghrelin, GHRP-2 is not lipogenic which means that it does not induce fat storage. 

Although ghrelin plays a large role in hunger, GHRP-2 as an analog of ghrelin does not increase 

appetite significantly.

GHRPs are not simply surrogates of GHRH, instead GHRP-6 is an artificial activator of a separate

newly discovered receptor called Secretagogue Receptor (GHS-R). Soon Ghrelin was discovered, the endogenous ligand that binds to the GHS-R. Both Ghrelin and all the synthetic compounds such as GHRP-6 were termed "Secretagogues" (GHSs). One side effect of GHRP-6 is a significant increase in appetite due to stimulating the release of Ghrelin, a peptide that is released naturally in the lining of

the stomach that increases hunger and gastric emptying. Also, GHRP-6 causes stimulation of the

anterior pituitary gland which causes an increase in release. The increased amounts of Hormone can cause the liver to secrete the hormone , which improves the animal body's ability to burn fat and build muscle. Since GHRP-6 acts directly on the feedback loop which signals the inhibition of Hormone

release, GHRP-6 can re-stimulate the production of  Hormone.

Polypeptide Hormones we supply

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