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Male Sex Hormones Injectable Polypeptide Gonadorelin Acetate

Male Sex Hormones Injectable Polypeptide Gonadorelin Acetate

  • Male Sex Hormones Injectable Polypeptide Gonadorelin Acetate
Male Sex Hormones Injectable Polypeptide Gonadorelin Acetate
Product Details:
Place of Origin: China manufactuer
Brand Name: Gonadorelin
Certification: ISO9001 14001
Model Number: 71447-49-9
Payment & Shipping Terms:
Minimum Order Quantity: 10 vails
Price: Negotiable
Packaging Details: Special disguised packaging or as your demand
Delivery Time: within 12hours after payment
Payment Terms: T/T, ,
Supply Ability: plent of stock
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Detailed Product Description
Category: Polypeptide Hormones CAS: 71447-49-9
Export Markets: Global Delivery: 4~7 Days Door-to-door
High Light:

sex steroid hormone

,

male hormones

What is Gonadorelin:

 

Gonadorelin is a medicine that is the same as gonadotropin-releasing hormone (GnRH) that is naturally released from the hypothalamus gland. GnRH causes the pituitary gland to release other hormones (luteinizing hormone [LH] and follicle-stimulating hormone [FSH]). LH and FSH control development in children and fertility in adults.

 

Quick details:

 

Product Name

Gonadorelin Acetate 

Sequence 

Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2

Unit packing 2mg/vial

Cas No. 

71447-49-9

Molecular Formula 

C55H75N17O13

Molecular Weight 

1182.3

Purity (HPLC)

98.0%min.

Appearance 

White powder

Single Impurity(HPLC) 

0.5%max

Amino Acid Composition 

±10% of theoretical

Peptide Content(N%)

 ≥80.0% 

Water Content(Karl Fischer) 

≤8.0%

Acetate Content(HPIC)

≤10.0%

Specific Rotation (20/D) 

-55.0~-65.0°(c=1 1%HAc)

MS(ESI)

 Consistent

Mass Balance 

95.0~105.0%

 

Description:

 

Gonadorelin is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pitutitary. In the pituitary GnRH stimulates synthesis and release of FSH and LH, a process that is controlled by the frequency and amplitude of GnRH pulses, as well as the feedback of androgens and estrogens. The pulsatility of GnRH secretion has been seen in all vertebrates, and it is necessary to ensure a correct reproductive function. Thus a single hormone, GnRH, controls a complex process of follicular growth, ovulation, and corpus luteum maintenance in the female, and spermatogenesis in the male. Its short half life requires infusion pumps for its clinical use.

 

Gonadorelin is used to test how well the hypothalamus and the pituitary glands are working. It is also used to cause ovulation (release of an egg from the ovary) in women who do not have regular ovulation and menstrual periods because the hypothalamus gland does not release enough GnRH.

 

Application:

 

Gonadorelin acetate is used by an animal’s body as a diagnostic aid that assists with hypothalamic-pituitary axis function. Some studies have also looked into the potential use of the synthesized version of this peptide as an infertility therapy agent. When produced by an animal’s body gonadorelin acetate acts as a natural gonadotropin releasing hormone (GnRH) which is primarily used as a means of synthesizing and releasing luteinizing hormone throughout the body from the anterior pituitary gland. This chemical can also act as a follicle stimulating hormone by increasing production of this chemical, though research has indicated that this behavior occurs to a much lesser degree.

 

Usage:

 

Synthetic luteinizing hormone–releasing hormone; used as the acetate or hydrochloride salt in evaluation of hypogonadism and as the acetate salt in the treatment of delayed puberty, infertility, and amenorrhea.

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