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Local Anesthetic Raw Powder Pramoxine Hydrochloride / Pramoxine HCl 637-58-1

Place of Origin china manufactuer
Brand Name SBJ
Certification Enterprise Standard
Model Number 637-58-1
Minimum Order Quantity 10g
Price $1unit
Packaging Details A small amount of camouflage package, with a large number of commodity exchange the product name on the invoice into other products which easy pass customs or by sea.
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Product Details
EINECS 211-293-1 CAS NO. 637-58-1
Molecular Formula C17H28ClNO3 Molecular Weight 329.8621
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Product Description

Local Anesthetic Raw Powder Pramoxine Hydrochloride / Pramoxine HCl 637-58-1


Pramoxine Hydrochloride

 

Pramoxine Hydrochloride product name: pramoxine hydrochloride

Pramoxine Hydrochloride Other name:4-(3-(p-butoxyphenoxy)propyl)-morpholinhydrochloride 
gamma-morpholinopropyl4-n-butoxyphenyletherhydrochloride
p-butoxyphenylgamma-morpholinopropyletherhydrochloride 
proctofoam; PRAMOXINE HCL , PRAXOMINE HYDROCHLORIDE
TRONOTHANE HYDROCHLORIDE , 4-[3-(P-BUTOXYPHENOXY)PROPYL]MORPHOLINE HYDROCHLORIDE, 4-n-butoxyphenyl gamma-morpholinopropyl ether hydrochloride 
4-N-BUTOXYPHENYL G-MORPHOLINOPROPYL ETHER HYDROCHLORIDE, pramocaine hydrochloride , PRAMOXINE HCL USP, TRONOTHANE HYDROCHLORIDE USP

Pramoxine Hydrochloride EINECS: 211-293-1

Pramoxine Hydrochloride CAS NO. 637-58-1

Pramoxine Hydrochloride Appearance: white or off white crystalline powder 

Pramoxine Hydrochloride Assay: between 98.0% and 102.0% 

Pramoxine Hydrochloride Standard: USP31 STANDARD

Pramoxine Hydrochloride Molecular formula: C17H28ClNO3

Pramoxine Hydrochloride Molecular Weight: 329.8621

Pramoxine Hydrochloride Uses: local anesthetics

 

Melting range 170~174°C 171.7~173.2°C
Loss on drying ≤1.0% 0.12%
Residue on ignition ≤0.1% 0.04%
Ethanol ≤0.5% 0.061%
Carbinol ≤0.3% 0.10%
Acetone ≤0.5% Not detected
Assay 98.0%~102.0% 99.98%
Conclusion The results conforms with USP33

 


Description

 

1. Pramocaine (INN and BAN, also known as pramoxine or pramoxine HCI) is a topical anesthetic
discovered at Abbott Laboratories in 1953 and used as an antipruritic. Chemically, it is p-n
butoxyphenyl gammamorpholinopropyl ether hydrochloride. During research and development,
pramoxine hydrochloride stood out among a series of alkoxy aryl alkamine ethers as an especially
good topical local anesthetic agent.
 
2. Pharmacologic study revealed it to be potent and of low acute and subacute toxicity, well tolerated by
 most mucous membranes and of a low sensitizing index in man. Like other local anesthetics,
paramoxine decreases the permeability of neuronal membranes to sodium ions, blocking both initiation
 and conduction of nerve impulses. Depolarization and repolarization of excitable neural membranes
is thus inhibited, leading to numbness.
 


Usages

 

1. Topical anesthetics are used to relieve pain and itching caused by conditions such as sunburn or
other minor burns, insect bites or stings, poison ivy, poison oak, poison sumac, and minor cuts and
scratches. Pramocaine and dibucaine are also common ingredients in over the counter hemorrhoid preparations.


2. Muscle relaxant (smooth)and slows growth of unwanted facial hair.

 


Related Product

 

Local Anesthetic Series
Linocaine HCl CAS No.: 6108-05-0
Propitocaine HCl CAS No.: 1786-81-8
Tetracaine HCl CAS No.: 136-47-0
Benzocaine CAS No.: 94-09-7
Prilocaine CAS No.: 721-50-6
Procaine CAS No.: 59-46-1
Pramoxine HCl CAS No.: 637-58-1
Procainamide HCl CAS No.: 614-39-1
Ropivacaine HCl CAS No.: 98717-15-8
Dibucaine HCl CAS No.: 61-12-1
Bupivacaine HCl CAS No.: 14252-80-3
Levobupivacaine HCl CAS No.: 27262-48-2

 


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Local Anesthetic Drugs Bupivacaine HCl White Powder 14252-80-3