Place of Origin: | China |
Brand Name: | www.steroidaily.com |
Certification: | ISO9001 |
Model Number: | 50-02-2 |
Minimum Order Quantity: | 10g |
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Price: | 1USD/G |
Packaging Details: | foil bag or tin |
Delivery Time: | 5~7 work days |
Payment Terms: | T/T, , |
Supply Ability: | 50000kg/month |
CAS: | 50-02-2 | EINECS: | 200-003-9 |
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MF: | C22H29FO5 | MW: | 392.46 |
Apperance: | White Crystalline Powder | Manufacturer: | Shuangbojie |
MP: | 262-264°C | Assay: | 98% |
Email: | Service01@chembj.com | ||
High Light: | anti inflammatory steroid,legal testosterone steroids |
Powder Dexamethasone Acetate Anti - Inflammatory Hormone Cas 50-02-2
Product name | Dexamethasones |
Other name | 16-alpha-methyl-9-alpha-fluoro-1,4-pregnadiene-11-beta,17-alpha,21-triol-3,2 |
CAS register number | 50-02-2 |
EINECS | 200-003-9 |
Molecular formula | C22H29FO5 |
Appearance | White crystalline powder |
Molecular weight | 392.46 |
Manufacturer | Shuangbojie |
Melting point | 262-264°C |
Assay | 98% |
Usage | A glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth , and differentiation . Inhibits the induction of nitric oxide synthase |
Description of Dexamethasones:
1.Active Pharmaceutical Ingredients Dexamethasones is used to treat many inflammatory and autoimmune conditions , such as rheumatoid arthritis and bronchospasm . Idiopathic thrombocytopenic purpura , a decrease in numbers of platelets due to an immune problem , responds to 40 mg daily for four days ; it may be administered in 14-day cycles . It is unclear whether dexamethasones in this condition is significantly better than other glucocorticoids.
2.It is also given in small amounts before and/or after some forms of dental surgery , such as the extraction of the wisdom teeth , an operation which often leaves the patient with puffy, swollen cheeks.
COA:
Product name | Dexamethasones | |
Appearance | White crystalline powder | |
Specific optical rotation | Between+72°and +80° | +76.4° |
Chromatographic purity | Any individual impurity not more than 1.0% Total impurities not more than 2.0% |
0.46% 1.13% |
Loss on drying | Not more than 0.5% | 0.11% |
Residue on ignition | Not more than 0.2% | 0.06% |
Residual solvents | Methanol≤3000ppm Methylene Chloride≤600ppm |
364ppm Not detect out Not detect out Not detect out |
Assay | Between 97.0% and 102.0% | 98.1% |
Micronixation | 90% not more than 10 microns | 90% not more than 10 aicrons |
Applications of Dexamethasones:
1.It is injected into the heel when treating plantar fasciitis, sometimes in conjunction with triamcinolone acetonide.
2.It is useful to counteract allergic anaphylactic shock , if given in high doses.
3.It is present in certain eye drops - particularly after eye surgery - and as a nasal spray (trade name Dexacort) , and certain ear drops (Sofradex, when combined with an antibiotic and an antifungal) . Dexamethasones intravitreal steroid implants (trade name Ozurdex) have been approved by the FDA to treat ocular conditions such as diabetic macular edema , central retinal vein occlusion, and uveitis.
4.Dexamethasones is used in transvenous screw-in cardiac pacing leads to minimize the inflammatory response of the myocardium . The steroid is released into the myocardium as soon as the screw is extended and can play a significant role in minimizing the acute pacing threshold due to the reduction of inflammatory response . The typical quantity present in a lead tip is less than 1.0 mg.
5.Dexamethasones is often administered before antibiotics in cases of bacterial meningitis . It then acts to reduce the inflammatory response of the body to the bacteria killed by the antibiotics (bacterial death releases proinflammatory mediators that can cause a response which is harmful to the patient), thus improving prognosis and outcome.
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