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Synonym N-Acetyl-4-ethoxyaniline, N-Acetyl-p-phenetidine, 4'-Ethoxyacetanilide
mp: 134.0 to 138.0 deg-C
bp: 132 °C / 4mmHg
storage temp.: 2-8°C
form: white powder
Water Solubility: 0.076 g/100 mL
Usage: Analgesic, antipyretic.
Stability: Stable. Incompatible with strong oxidizing agents, strong acids.
Keywords: Fenacetina, phenacetin, Phenacetine, Phenacetinum
Phenacetin was the first NSAID and fever reducer to go on the market. Its analgesic effects are due to its actions on the sensory tracts of the spinal cord. In addition, phenacetin has a depressant action of the heart, where it acts as a negative inotrope. It is an antipyretic, acting on the brain to decrease the temperature set point. It is also used to treat rheumatoid arthritis (subacute type), intercostal neuralgia, and some forms of ataxia.
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