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|Molecular Formula:||C14H22N2O||Molecular Weight:||234.34|
|Use:||Local Anesthetics||Payment Terms:||Western Union, MoneyGram, T/T,Bitcoin|
|Delivery Time:||Within 12hours After Payment||Delivery:||EMS, DHL, FedEx, Express Courier.|
top purity Lidocaine CAS 137-58-6 Pharmaceutical Raw Materials Topical Anesthetic And Treatment
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. Melting point: 66-69C
. Flash point:166C
. Boiling point:350.8C at 760 mmHg
. Water solubility:practically insoluble
. Vapour Pressure:4.28E-05mmHg at 25C
Lidocaine is used topically to relieve itching, burning, and pain from skin inflammations,
injected as a dental anesthetic, or as a local anesthetic for minor surgery.It is on the World
Health Organization's List of Essential Medicines, a list of the most important
medications needed in a basic healthcare system.
treatment of ventricular arrhythmias (for acute myocardial infarction, digoxin poisoning, cardioversion,
or cardiac catheterization) if amiodarone is not available or contraindicated. Lidocaine should
be given for this indication after defibrillation, CPR, and vasopressors have been initiated.
A routine prophylactic administration is no longer recommended for acute cardiac infarction;
the overall benefit of this measure is not convincing.
Mechanism of action: Lidocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses, thereby effecting local anesthetic action.Hemodynamics:
Excessive blood levels may cause changes in cardiac output, total peripheral resistance, and mean arterial pressure. With central neural blockade these changes may be attributable to block of
autonomic fibers, a direct depressant effect of the local anesthetic agent on various components of
the cardiovascular system and/or the beta-adrenergic receptor stimulating action of epinephrine when present. The net effect is normally a modest hypotension when the recommended dosages are not exceeded.
and intermediate duration of efficacy. Therefore, lidocaine is suitable for infiltration, block, and
surface anesthesia. Longer-acting substances such as bupivacaine are sometimes given
preference for subdural and epidural anesthesias; lidocaine, though, has the advantage
of a rapid onset of action.
almost doubling the duration of anaesthesia. For surface anesthesia, several available formulations
can be used e.g. for endoscopies, before intubations, etc. Buffering the pH of lidocaine makes local
freezing less painful. Lidocaine drops can be used on the eyes for short ophthalmic procedures.
insensitivity to lidocaine has been described in people who also have attention deficit hyperactivity
disorder.In dental anesthesia, a relative insensitivity to lidocaine can occur for anatomical reasons
due to unexpected positions of nerves. Some people with Ehlers-Danlos syndrome are insensitive
treating jellyfish stings, both numbing the affected area and preventing further nematocyst discharge
Lidocaine patches are used to relieve the pain of post-herpetic neuralgia (PHN; the burning, stabbing pains, or aches that may last for months or years after a shingles infection). Lidocaine is in a class of medications called local anesthetics. It works by stopping nerves from sending pain signals.
Lidocaine is used on different parts of the body to cause numbness or loss of feeling for patients having certain medical procedures. It is also used to relieve pain and itching caused by conditions such as sunburn or other minor burns, insect bites or stings, poison ivy, poison oak, poison sumac, minor cuts, or scratches.
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