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|Grade Standard:||Pharmaceutical Grade||Purity:||99%|
Product Name. ACE-031
Unit size. 1 mg/vial
CAS NO. 307297-39-8
Purity: ≥95% (HPLC)
Physical State. Lyophilized Powder
Solubility. Soluble in water or 1% acetic acid
Storage. Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18°C. Upon reconstitution of the peptide it should be stored at 4°C between 2-21 days and for future use below -18°C.
Usage: ACE-031 is a soluble form of activin receptor type IIB (ActRIIB). ACE-031 promotes muscle growth by binding to myostatin and other negative regulators of muscle mass. Ace-031, also known as ACVR2B, is a soluble form of activin type IIB receptor, which is an inhibitor of myostatin and other naturally occurring proteins that limit muscle growth. This compound was genetically developed to bind to myostatin before it can attach to its receptor and halt muscle growth.
|Storage temperature:||2-8 Celsius degree|
|Quality guarantee period:||2 years in 2-8 Celsius degree|
|Vial color:||transparent color / Top color: blue/green/red/yellow/ customized|
|Physical Appearance:||freeze-dried powder in white|
|Place of origin:||China|
|Delivery Time:||Within 24 hours After receive your payment|
|Payment Method:||Western Union, MoneyGram, T/T, Aliexpress|
ACE-031 is an investigational protein therapeutic that builds muscle and increases strength by inhibiting molecules that bind to and signal through a cell surface receptor called Activin Receptor Type IIB (ActRIIB). ACE-031 is a recombinant fusion protein that is produced by joining a portion of the human ActRIIB receptor to a portion of a human antibody. This creates a freely circulating, decoy version of ActRIIB which removes proteins, such as GDF-8 (myostatin) and other related molecules that limit the growth and strength of muscle.
ACE-031 belongs to class of proteins of TGF-beta super family that regulate muscle growth. ACE-031 acts on the molecular switches of these molecules and promote muscle growth. In experimental studies, ACE-031 promotes muscle growth and inhibits ActRIIB receptor signaling. In pre-clinical studies, administration of ACE-031 for two weeks increased skeletal muscle density, decreased leptin levels, and increased adiponectin.